TCT-359 Predictors associated with Major Adverse Cardiac Events following Successful Chronic Total Occlusion Intervention with Drug-eluting Stents

• Sang-Ho Park¹, 
• Seung-Woon Rha², 
• Jin-Soo Byun¹, 
• Ung Jun¹, 
• Se-Whan Lee¹, 
• Won-Yong Shin¹, 
• Seung Jin Lee¹, 
• Dong-Kyu Jin¹, 
• Byoung Geol Choi², 
• Jin oh Na², 
• Cheol Ung Choi², 
• Hong Euy Lim², 
• Jin Won Kim², 
• Eung Ju Kim², 
• Chang Gyu Park², 
• Hong Seog Seo², 
• Dong Joo Oh²

• ¹ Soonchunhyang University Cheonan Hospital, Cheonan, Korea, Republic of
• ² Cardiovascular Center, Korea University Guro Hospital, Seoul, Korea, Republic of

Background

There is limited evidence regarding predictors associated with clinical outcomes of patients with chronic total occlusion (CTO) successfully treated with drug-eluting stents (DESs).

Methods

We investigated the 249 patients (pts) with de novo CTO lesions successfully treated with DESs from 2004 to 2010. All major adverse cardiovascular events (ALL-MACEs) were defined as composite of total death, any myocardial infarction (MI), target vessel revascularization (TVR) and non-target vessel revascularization. The association of ALL-MACEs with clinical, biochemical and procedural variables were examined.

Results

The 12-month follow-up has been performed in the 242 of 249 pts (97.2%). The incidence of ALL-MACEs was the 40 of 242 patients (16.5%). Multivariate logistic regression was used to identify predictors affecting 1-year ALL-MACE. Left main involvement was significantly associated with 1-year ALL-MACEs and prior PCI history had a trend to be associated with 1-year ALL-MACEs (Table).

Conclusions

In our study, left main involvement was an important independent predictor associated with 1-year MACE following successful CTO intervention with DES.